Deamination of Serine
نویسنده
چکیده
In an investigation of transamination reactions between pyridoxal and amino acids at 100” (2) serine was found to behave anomalously, apparently being deaminated to pyruvic acid with little change in pyridoxal concentration. Although serine is known to be deaminated by hot concentrated alkalies (3) and acids (4), such a non-enzymatic reaction in the pH range near neutrality has not been reported. This reaction has now been studied in some detail and has been shown to require both pyridoxal and a metal salt for its catalysis. Cysteine undergoes a similar reaction to yield pyruvate, ammonia, and hydrogen sulfide.
منابع مشابه
Factors influencing bacterial deamination: Factors influencing the activity of dl-serine deaminase in Bacterium coli.
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